Our laboratory is interested in the genetic analysis of vertebrate visual system development and function, with a focus on the retina.
The retina, which is a part of the nervous system, is well suited for studying brain function due to its accessibility. In our studies, we use the zebrafish, a small teleost native to tropic regions of the Indian peninsula.
This increasingly popular model organism offers a number of experimental advantages, such as easy maintenance, high fecundity, transparent embryos, and rapid embryological development.
Importantly, strains carrying mutations and transgenes can efficiently be constructed by CRISPR/Cas9 genome editing and transposon based transgenesis.