July 2017: Stephan Neuhauss the new Vice-Dean for Research and Planning
Congratulations (or Condolences) to Stephan for being elected to become Vice-Dean for Research and Planning of the Faculty of Science, beginning in August 2017.
Good luck and may you make more new friends than enemies.
July 2017: Congratulations to Stephanie (Steffi) Niklaus
Steffi defended her thesis with flying colors, leaving her committee speechless.
All the best of fun for the well-deserved extend trip around the world.
We are happy that you will not leave us yet and will come back to finish and write even more papers.
Proud "Doktorvater" and your team
Latest Publications June/July 2017:
Fish Larvae on Cocaine
Steffi just published the curious finding that cocaine accumulation in the zebrafish eye leads to an increased response of the retina to light. This may be related to changes in light adaptation connected to dopamine signaling. Find the open access link to this single observation see open access at:
Cocaine Accumulation in Zebrafish Eyes Leads to Augmented Amplitudes in the Electroretinogram
Glutamate Transport at the Photoreceptor Synapse Shape Neurotransmission
With perfect timing just before the submission of her thesis, Steffi, Lucia and friends got the long awaited EAAT2 story published. These two paralogs of glutamate transporters represent prime example of subfunctionalization of an ancient gene function. They found that glial-expressed EAAT2a is the main glutamate sink at the cone photoreceptor synapse. EAAT2b in turn is expressed on cone photoreceptors, sporting a large anion leak current, effectively clamping the photoreceptor resting potential. Read the paper for free clicking the link below.
Shaping of Signal Transmission at the Photoreceptor Synapse by EAAT2 Glutamate Transporters.
Niklaus S, Cadetti L, Vom Berg-Maurer CM, Lehnherr A, Hotz AL, Forster IC, Gesemann M, Neuhauss SCF.
Evolutionary Conservation in the Vertebrate Kidney
Our former PhD student Yuya Sugano published yet another paper from our fruitful collaboration with the Loffing lab from the Institute of Anatomy. In this paper he shows that gene expression is conserved between the mammalian distal convoluted tubule and the zebrafish distal late segment. Interestingly some genes enriched in the mouse are not found to be enriched in the zebrafish. Instead, related homologous genes from the fish are enriched, likely fulfilling a similar function.
Comparative transcriptomic analysis identifies evolutionarily conserved gene products in the vertebrate renal distal convoluted tubule.
Sugano Y, Cianciolo Cosentino C, Loffing-Cueni D, Neuhauss SCF, Loffing J.
Pflugers Arch. 2017 Jun 27. doi: 10.1007/s00424-017-2009-8
June 2017: Congratulations Dr. Irene Ojeda Naharros
Congratulations to Irene Ojeda Naharros, our newly minted Dr.sc.nat.
Triple digits of hours tracking fluorescent particles in photoreceptor cells have paid off.
All the best of luck for your postdoc and your growing family!
June 2017: Congratulations to Selin Ozgur
Selin finished her Master in Genetics this May working on camta1 mutants. We will miss your ready smile and your comedian’s talent that made our lunch breaks. All the best for your graduate school applications.
May 2017: New webpage for the group of Ruxandra Bachmann
Ruxandra Bachmann has a new homepage:
Congratulations Ruxandra Bachmann!!!
We are proud and happy to report that Ruxandra got awarded the very prestigious SNF Förderprofessorship of the Swiss National Science Foundation. From this fall on she will be an independent assistant professor at the Institute of Molecular Genetics. Luckily she will continue to be associated with us via her fish work. Incidentally I started my academic career with the same professorship. Congratulations and all the best for starting your completely independent research team.
Congratulation Dr. Stella Glasauer
Proud „Doktorvater“ with Stella Glasauer at the graduation ceremony in October 2016
It's over - 2nd European Meeting on Phototransduction
The 2nd European Meeting on Phototransduction which took place in September 2016 on the beautiful Monte Verita in Ascona was a full success. The 50 participants from 12 different countries presented and discussed photoransduction in all its depth from biophysical properties to evolution and diseases.
Yuya Sugano: best thesis prize- Swiss society for anatomy
Yuya Sugano was awarded the best thesis prize at the annual meeting of the Swiss society for anatomy. Congratulations to this well-deserved honor.
Some part of the thesis is published in Kidney Int. 2015 Nov;88(5):1047-56 (Sugano et al; The Rho-GTPase binding protein IQGAP2 is required for the glomerular filtration barrier)
2nd European Meeting on Phototransduction
cover Journal of Comparative Neurology Vol.524 / No.12
new paper out
mglur6b:EGFP Transgenic zebrafish suggest novel functions of metabotropic glutamate signaling in retina and other brain regions
cover in Open Biology 2015 August
The Neuhauss Lab on TV
SRF Einstein Episode from 21.04.2011 about Zebrafish science in Zurich.