News

July 2017: Stephan Neuhauss the new Vice-Dean for Research and Planning

 

Congratulations (or Condolences) to Stephan for being elected to become Vice-Dean for Research and Planning of the Faculty of Science, beginning in August 2017.

Good luck and may you make more new friends than enemies.

July 2017: Congratulations to Stephanie (Steffi) Niklaus

defense steffi

 

Steffi defended her thesis with flying colors, leaving her committee speechless.

All the best of fun for the well-deserved extend trip around the world.

 

We are happy that you will not leave us yet and will come back to finish and write even more papers.

Proud "Doktorvater" and your team

Latest Publications June/July 2017:

 

Fish Larvae on Cocaine

Steffi just published the curious finding that cocaine accumulation in the zebrafish eye leads to an increased response of the retina to light. This may be related to changes in light adaptation connected to dopamine signaling. Find the open access link to this single observation see open access at:

steffi cocaine paper

Cocaine Accumulation in Zebrafish Eyes Leads to Augmented Amplitudes in the Electroretinogram

https://www.sciencematters.io/articles/201703000003

 

Glutamate Transport at the Photoreceptor Synapse Shape Neurotransmission

With perfect timing just before the submission of her thesis, Steffi, Lucia and friends got the long awaited EAAT2 story published. These two paralogs of glutamate transporters represent prime example of subfunctionalization of an ancient gene function. They found that glial-expressed EAAT2a is the main glutamate sink at the cone photoreceptor synapse. EAAT2b in turn is expressed on cone photoreceptors, sporting a large anion leak current, effectively clamping the photoreceptor resting potential. Read the paper for free clicking the link below. 

eaat 2 steffi

Shaping of Signal Transmission at the Photoreceptor Synapse by EAAT2 Glutamate Transporters.

Niklaus S, Cadetti L, Vom Berg-Maurer CM, Lehnherr A, Hotz AL, Forster IC, Gesemann M, Neuhauss SCF.

http://www.eneuro.org/content/4/3/ENEURO.0339-16.2017

 

Evolutionary Conservation in the Vertebrate Kidney

Our former PhD student Yuya Sugano published yet another paper from our fruitful collaboration with the Loffing lab from the Institute of Anatomy. In this paper he shows that gene expression is conserved between the mammalian distal convoluted tubule and the zebrafish distal late segment. Interestingly some genes enriched in the mouse are not found to be enriched in the zebrafish. Instead, related homologous genes from the fish are enriched, likely fulfilling a similar function.

yuya paper

Comparative transcriptomic analysis identifies evolutionarily conserved gene products in the vertebrate renal distal convoluted tubule.

Sugano Y, Cianciolo Cosentino C, Loffing-Cueni D, Neuhauss SCF, Loffing J.

Pflugers Arch. 2017 Jun 27. doi: 10.1007/s00424-017-2009-8

June 2017: Congratulations Dr. Irene Ojeda Naharros

irene

 

Congratulations to Irene Ojeda Naharros, our newly minted Dr.sc.nat.

Triple digits of hours tracking fluorescent particles in photoreceptor cells have paid off.

All the best of luck for your postdoc and your growing family!

June 2017: Congratulations to Selin Ozgur

selin

 

Selin finished her Master in Genetics this May working on camta1 mutants. We will miss your ready smile and your comedian’s talent that made our lunch breaks. All the best for your graduate school applications. 

May 2017: New webpage for the group of Ruxandra Bachmann

Congratulations Ruxandra Bachmann!!!

fireworks

 

We are proud and happy to report that Ruxandra got awarded the very prestigious SNF Förderprofessorship of the Swiss National Science Foundation. From this fall on she will be an independent assistant professor at the Institute of Molecular Genetics. Luckily she will continue to be associated with us via her fish work. Incidentally I started my academic career with the same professorship. Congratulations and all the best for starting your completely independent research team. 

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Congratulation Dr. Stella Glasauer

 

Proud „Doktorvater“ with Stella Glasauer at the graduation ceremony in October 2016

It's over - 2nd European Meeting on Phototransduction

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The 2nd European Meeting on Phototransduction which took place in September 2016 on the beautiful Monte Verita in Ascona was a full success. The 50 participants from 12 different countries presented and discussed photoransduction in all its depth from biophysical properties to evolution and diseases. 

 

Yuya Sugano: best thesis prize- Swiss society for anatomy

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Yuya Sugano was awarded the best thesis prize at the annual meeting of the Swiss society for anatomy. Congratulations to this well-deserved honor.

 

Some part of the thesis is published in Kidney Int. 2015 Nov;88(5):1047-56 (Sugano et al;  The Rho-GTPase binding protein IQGAP2 is required for the glomerular filtration barrier)

https://www.ncbi.nlm.nih.gov/pubmed/26154927 

2nd European Meeting on Phototransduction

trs

 

2nd European meeting on Phototransduction from September 04 - 07, 2016 to be held at the Conference Centre Monte Verita in Switzerland

https://www.uni-oldenburg.de/2nd-emp/

 

Organizers:
Stephan Neuhauss
Karl-Wilhelm Koch

Stella Glasauer

 cover Journal of Comparative Neurology Vol.524 / No.12

http://onlinelibrary.wiley.com/doi/10.1002/cne.24049/epdf

 

stella

new paper out

mglur6b:EGFP Transgenic zebrafish suggest novel functions of metabotropic glutamate signaling in retina and other brain regions

 

full article:

http://onlinelibrary.wiley.com/doi/10.1002/cne.24029/full

ncbi database:

https://www.ncbi.nlm.nih.gov/pubmed/27121676

 

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The Neuhauss Lab on TV

SRF Einstein Episode from 21.04.2011 about Zebrafish science in Zurich.