Microtubules are needed for nuclear targeting of incoming Ad2.  CLSM micrographs of texas red labeled Ad2 in HeLa cells treated with microtubule-directed drugs.  Nuclear envelope is indicated by an anti-lamin A,B,C immunostaining (right panel).  Modified from (1).

(1). Suomalainen, M., et al. (1999) J. Cell Biol 144: 657-672