Prof. Dr. Ernst Hafen

       


Curriculum Vitae
Publications
Groupmembers / Alumni
                 Institute for Molecular Systems Biology (IMSB)
ETH Zürich
Wolfgang-Pauli-Strasse 16
CH-8093 Zürich
Switzerland
IMSB Website
       

Growth control and signal transduction

We study the mechanisms of cell communication that control the growth and differentiation of multicellular organisms. Over the past several years, we have discovered a number of intracellular signaling pathways that are highly conserved between invertebrates and vertebrates. Aberrant regulation of these pathways in humans is associated with diseases such as cancer and diabetes. In our current research we use genetics, molecular biology and cell biology to address three specific questions:          
  1. How is cell and organ growth regulated during development?
  2. How are changes in cell shape coordinated during development?
  3. How can the activation of a single signal transduction pathway elicit different cellular responses?