Institute of Molecular Biology - University of Zürich

Abstracts - Charles Weissmann


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Astrocyte-specific expression of hamster prion protein (PrP) renders PrP knockout mice susceptible to hamster scrapie

A. J. Raeber, R .E. Race, S. Brandner, S .A. Priola, A. Sailer, R .A. Bessen, L. Mucke, J. Manson, A. Aguzzi, M. B. A. Oldstone, C. Weissmann, and B. Chesebro.

 

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Cellular & Molecular Life Sciences 53, 485-495 (1997)

Tracking prions: the neurografting approach

A. Aguzzi, T. Blattler, M. A. Klein, A. J. Raber, I: Hegyi, R. Frigg, S. Brandner, and C. Weissmann.

 

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Journal of Neurovirology 3, Suppl 1:23-24 (1997)

Neurotoxicity and neuroinvasiveness of prions

A. Aguzzi, A. Raeber, T. Blattler, E. Flechsig, M. Klein, C. Weissmann and S. Brandner.

 

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Proc.Natl.Acad.Sci.USA 94, 3279-3283 (1997)

A double-stranded RNA-activated protein kinase-dependent pathway mediating stress-induced apoptosis

S. D. Der, Y.-L. Yang., C. Weissmann, and B. R. G. Williams.

 

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Int. J. Exptl. Pathol. 77, 283-293. ()

The use of transgenic mice in the investigation of transmissible spongiform encephalopathies

C. Weissmann, M. Fischer, A. Raeber, H. Büeler, A. Sailer, D. Shmerling, T. Rülicke, S. Brandner, and A. Aguzzi.

 

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EMBO J. 16, 406 (1997)

Deficient cytokine signalling in mouse embryo fibroblasts with a targeted deletion in the PKR gene: role of IRF-1 and NFkB

A .Kumar, Y.-L. Yang, V. Flati, S. Der, S. Kadereit, J. Haque, A. Deb, L. Reis, C. Weissmann and B. R. G. Williams.

 

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Nature 383, 666-667 (1996)

Bovine spongiform Encephalopathy: A suspicious signature

A. Aguzzi and C. Weissmann

 

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Proc. Natl. Acad. Sci. USA 93, 13148-13151 (1996)

Normal host prion protein (PrPc) is required for scrapie spread within the central nervous system

S. Brandner, A. Raeber, A. Sailer, T. Blättler, M. Fischer, C. Weissmann and A. Aguzzi.

 

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LXI, Cold Spring Harbor Symp. LXI 511-522

The role of PrP in the pathogenesis of experimental scrapie. Cold Spring Harbor Symp.

C. Weissmann, M. Fischer, A. Raeber, H. Büeler, A. Sailer, D. Shmerling, T. Rülicke, S. Brandner, and A. Aguzzi.

 

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Naturw.Rundschau 49, 211-214 (1996)

Prionen: Neuartige Krankheitserreger

C. Weissmann

 

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FEBS Lett. 389, 3-11 (1996)

Molecular biology of transmissible spongiform encephalopathies.

C. Weissmann

 

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Proc. Natl. Acad. Sci. USA 93, 6158-6162 (1996)

Generation of mice with a 200-kb amyloid precursor protein (APP) gene deletion by Cre recombinase-mediated site-specific recombination in embryonic stems cells.

Z.-W. Li, G. Stark, J. Goetz, T. Rülicke, U. Müller and C. Weissmann.

 

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Trends in Microbiology 4, 129-131 (1996)

Sleepless in Bologna: Transmission of fatal familial insomnia.

A. Aguzzi and C. Weissmann.

 

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Nature 379, 339-343. (1996).

No neurotoxicity in PrP-deficient mice chronically exposed to PrPSc released by scrapie-infected neuroectodermal grafts.

S. Brandner, S. Isenmann, A. Raeber, M. Fischer, A. Sailer, Y. Kobayashi, S. Marino, C. Weissmann and A. Aguzzi.

 

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EMBO J. 15, 1255-1264 (1996)

Prion protein (PrP) with amino terminal deletions restoring susceptibility of PrP knockout mice to scrapie.

M. Fischer, T. Rülicke, A. Raeber, A. Sailer, M. Moser, B. Oesch, S. Brandner, A. Aguzzi and C. Weissmann.

 

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EMBO J. 14, 6095-6106 (1995)

Deficient signalling in mice devoid of double-stranded RNA-dependent protein kinase, PKR

Y.-L. Yang, L. F. L. Reis, J. Pavlovic, A. Aguzzi, R. Schäfer, A. Kumar, B. R. G. Williams, M. Aguet and C. Weissmann.

 

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Nature 375, 628-629 (1995)

Yielding under the strain

C. Weissmann

 

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Last updated 10-29-97 / Thomas Gutjahr