Hassan Fazilaty

Postdoctoral fellow

Dr. Hassan Fazilaty

Office Y55-L-70

Tel +41 44 635 31 26

Brief CV

08.2019-present, Postdoctoral fellow, Lab of Professor Konrad Basler, Institute of Molecular Life Sciences, University of Zurich, Zürich, Switzerland

04.2019-08.2019, Postdoctoral researcher, Lab of Professor M. Angela Nieto, Instituto de Neurociencias CSIC-UMH, San Juan de Alicante, Spain

09.2014-04.2019, Doctor of Philosophy (Ph.D.), Lab of Professor M. Angela Nieto, Instituto de Neurociencias CSIC-UMH, San Juan de Alicante, Spain &  School of Medicine, Universidad Autonoma de Madrid (UAM), Madrid, Spain

09.2011-08.2014, Master of Science (M.Sc.) in Human Genetics, Department of Medical Genetics, Tehran University of Medical Sciences (TUMS), Tehran, Iran

Research

09.2014-07.2019, Research scholar, Instituto de Neurociencias CSIC-UMH, San Juan de Alicante, Spain

05.2013-08.2014, Clinical Genetics research scholar, Genetic unit, eye research center, Rasoul Akram Medical Complex, Tehran, Iran

01.2013-08.2014, Research scholar, National Institute of Genetic Engineering and Biotechnology, Tehran, Iran

Fellowship/funding

12.2021-11.2021, Forschungskredit Postdoc fellowship, University of Zurich, Zurich, Switzerland

08.2021, 2 years 3RCC grant (Project OC-2020-011) to Jamie Little, Konrad Basler, Erich Brunner and Hassan Fazilaty, Switzerland

11.2019-11.2021, 2 years fellowship of Cancer Research Center Zurich (CRC funding) to Prof. Konrad Basler and Prof. Gerhard Rogler, University of Zurich (UZH) and University Hospital Zurich (USZ), Switzerland

09.2014-08.2017, 3 years fellowship award, Santiago Grisolia (GRISOLIA / 2014/004) Resolution of 3 June 2014, Generalitat Valenciana, Alicante, Spain

08.2013, Grant # 92003378 from Iran National Science Foundation (INSF) to Dr. Babak Behnam and Hassan Fazilaty

06.2013, Grant from Iran University of Medical Sciences (IUMS) to Dr. Babak Behnam and Hassan Fazilaty

Selected Publications

Fazilaty H. Restoration of embryonic gene expression patterns in tissue regeneration and disease. Nat Rev Mol Cell Biol 2023 Feb 16. |https://10.1038/s41580-023-00586-y.

Fazilaty H*, Brügger M*, Valenta T* Szczerba BM, Berkova L, Doumpas N, Hausmann G, Scharl M and Basler K. Tracing colonic embryonic transcriptional profile and tracking their reactivation in inflammatory disease at single cell level. Cell Reports 36, 109484. 2021 Aug 03.  |https://doi.org/10.1016/j.celrep.2021.109484.

Brügger M*, Valenta T*, Fazilaty H*, Hausmann G, Basler K*. Distinct populations of crypt-associated fibroblasts act as signaling hubs to control colon homeostasis. Plos Biology 2020 Dec 11. |https://doi.org/10.1371/journal.pbio.3001032.

Fazilaty H, Rago L, Youssef KK, Ocana O, Garcia-Asencio F, Arcas A, Galceran J, Nieto MA. A Gene Regulatory Network to Control EMT Programs in Development and Disease. Nature Communication 2019 10:5115  |https://doi.org/10.1038/s41467-019-13091-8.

Rago L, Castroviejo N, Fazilaty H, Garcia-Asencio F, Galceran J, Nieto MA. MicroRNAs establish the right-handed dominance of the heart laterality pathway in vertebrates. Developmental Cell 2019 Oct 17. pii: S1534-5807(19)30768-3. | https://doi.org/10.1016/j.devcel.2019.09.012.

Fazilaty H, Gardaneh M, Akbari P, Zekri A, Behnam B. SLUG and SOX9 cooperatively regulate metastatic niche factors in breast cancer. Cancer Microenvironment. 2015 September doi: https://doi.org/10.1007/s12307-015-0176-8.

Fazilaty H, Mehdipour P*. Genetics of breast cancer bone metastasis; a sequential multistep pattern. Clinical & Experimental Metastasis. 2014 Jun;31(5):595-612. Epub 2014 Feb 4. |https://doi:10.1007/s10585-014-9642-9.

Fazilaty H, Gardaneh M, Bahrami T, Salmaninejad A, and Behnam B. Crosstalk between breast cancer stem cells and metastatic niche: emerging molecular metastasis pathway? Tumor Biology 2013 Aug; 34(4):2019-30. doi: https://doi.org/10.1007/s13277-013-0831-y.

*Equal contribution.

Book chapters

Behnam B, Fazilaty H, Roghanian A, The Importance of Circulating Tumor Cells and Tumor Models in Future of Cancer Therapy (book title: Ex Vivo Engineering of the Tumor Microenvironment, pp. 121-135, Editors Aref, A. and Barbie D. (eds.)). Springer International Publishing Switzerland 2017, DOI 10.1007/978-3-319-45397-2_7

Fazilaty H, Mehdipour P. Retinic Acid Receptor-beta, from gene to clinic. (In book: Epigenetics Territory and Cancer, pp.363-372, Editor Parvin Mehdipour). Springer Science+Business Media Dordrecht 2015. DOI 10.1007/978-94-017-9639-2_12

PubMed link: https://pubmed.ncbi.nlm.nih.gov/?term=fazilaty+h&sort=date