Publications

PubMed link to find all manuscripts

bioRxiv link to find all preprints by the lab

 

Lab members marked in bold.

 

2019:

A conserved regulatory program initiates lateral plate mesoderm emergence across chordates.
Prummel KD*, Hess C*, Nieuwenhuize S, Parker HJ, Rogers KW, Kozmikova I, Racioppi C, Brombacher EC, Czarkwiani A, Knapp D, Burger S, Chiavacci E, Shah G, Burger A, Huisken J, Yun MH, Christiaen L, Kozmik Z, Müller P, Bronner M, Krumlauf R, Mosimann C.
* equal contribution
Nat Commun. 2019 Aug 26;10(1):3857. doi: 10.1038/s41467-019-11561-7.
PMID: 31451684
 
Anterior trunk muscle shows mix of axial and appendicular developmental patterns.
Sagarin KA, Redgrave AC, Mosimann C, Burke AC, Devoto SH.
Dev Dyn. 2019 Oct;248(10):961-968. doi: 10.1002/dvdy.95. Epub 2019 Aug 16.
PMID: 31386244

Active receptor tyrosine kinases, but not Brachyury, are sufficient to trigger chordoma in zebrafish
D‘Agati G, Cabello EM, Frontzek K, Rushing EJ, Klemm R, Robinson MD, White RM, Mosimann C, Burger A.
Dis Model Mech. 2019 Jun 20. pii: dmm.039545. doi: 10.1242/dmm.039545. [Epub ahead of print].
PMID: 31221659

 

CRISPR-induced double-strand breaks trigger recombination between homologous chromosome arms.
Brunner E, Yagi R, Debrunner M, Beck-Schneider D, Burger A, Escher E, Mosimann C, Hausmann G, Basler K.
Life Sci Alliance. 2019 Jun 13;2(3). pii: e201800267. doi: 10.26508/lsa.201800267. Print 2019 Jun.
PMID: 31196871

A Hox-TALE regulatory circuit for neural crest patterning is conserved across vertebrates.
Parker HJ, De Kumar B, Green SA, Prummel KD, Hess C, Kaufman CK, Mosimann C, Wiedemann LM, Bronner ME, Krumlauf R.
Nat Commun. 2019 Mar 13;10(1):1189. doi: 10.1038/s41467-019-09197-8.
PMID: 30867425
 

 

2018:

Mutations in Bcl9 and Pygo genes cause congenital heart defects by tissue-specific perturbation of Wnt/beta-catenin signaling
Cantù C*, Felker A*, Zimmerli D*, Prummel KD, Cabello EM, Chiavacci E, Méndez-Acevedo KM, Kirchgeorg L, Burger S, Ripoll J, Valenta T, Hausmann G, Vilain N, Aguet M, Burger A, Panáková D, Basler K¹, Mosimann C¹.
*equal contribution; ¹co-senior authors
Genes Dev. 2018 Nov 1;32(21-22):1443-1458. doi: 10.1101/gad.315531.118. Epub 2018 Oct 26.
PMID: 30366904

 

Cre/lox-controlled spatio-temporal perturbation of FGF signaling in zebrafish.
Kirchgeorg L*, Felker A*, van Oostrom M, Chiavacci E, Mosimann C.
* equal contribution
Dev Dyn. 2018 Sep 8. doi: 10.1002/dvdy.24668. [Epub ahead of print]
PMID: 30194800

 

Cancer modeling by Transgene Electroporation in Adult Zebrafish (TEAZ).
Callahan SJ, Tepan S, Zhang YM, Lindsay H, Burger A, Campbell NR, Kim IS, Hollmann TJ, Studer L, Mosimann C, White RM.
Dis Model Mech. 2018 Jul 30. pii: dmm.034561. doi: 10.1242/dmm.034561. [Epub ahead of print].
PMID: 30061297

 

Planar cell polarity signalling coordinates heart tube remodelling through tissue-scale polarisation of actomyosin activity
Merks AM, Swinarski M, Meyer AM, Müller NV, Özcan I, Donat S, Burger A, Gilbert S, Mosimann C, Abdelilah-Seyfried S & Panáková D.
Nat Commun. 2018 Jun 4;9(1):2161. doi: 10.1038/s41467-018-04566-1.
PMID: 29867082.

 

Continuous addition of progenitors forms the cardiac ventricle in zebrafish.
Felker A, Prummel KD, Merks AM, Mickoleit M, Brombacher EC, Huisken J, Panáková D*, Mosimann C*.
^* co-senior authors
Nat Commun. 2018 May 21;9(1):2001. doi: 10.1038/s41467-018-04402-6.
PMID: 29784942

 

Switch and Trace: Recombinase Genetics in Zebrafish.
Carney TJ*, Mosimann C*.
^* co-senior authors
Trends Genet. 2018 Feb 8. pii: S0168-9525(18)30004-0. doi: 10.1016/j.tig.2018.01.004. [Epub ahead of print] Review.
PMID: 29429760

 

Tbx5a lineage tracing shows cardiomyocyte plasticity during zebrafish heart regeneration.
Sánchez-Iranzo H, Galardi-Castilla M, Minguillón C, Sanz-Morejón A, González-Rosa JM, Felker A, Ernst A, Guzmán-Martínez G, Mosimann C, Mercader N.
Nat Commun. 2018 Jan 30;9(1):428. doi: 10.1038/s41467-017-02650-6.
PMID: 29382818

 

2017:

Toddler signaling regulates mesodermal cell migration downstream of Nodal signaling.
Norris ML, Pauli A, Gagnon JA, Lord ND, Rogers KW, Mosimann C, Zon LI, Schier AF.
Elife. 2017 Nov 9;6. pii: e22626. doi: 10.7554/eLife.22626.
PMID: 29117894

 

Highly efficient DNA-free gene disruption in the agricultural pest Ceratitis capitata by CRISPR-Cas9 ribonucleoprotein complexes.
Meccariello A, Monti SM, Romanelli A, Colonna R, Primo P, Inghilterra MG, Del Corsano G, Ramaglia A, Iazzetti G, Chiarore A, Patti F, Heinze SD, Salvemini M, Lindsay H, Chiavacci E, Burger A, Robinson MD, Mosimann C, Bopp D, Saccone G.
Sci Rep. 2017 Aug 30;7(1):10061. doi: 10.1038/s41598-017-10347-5.
PMID: 28855635

 

A defect in the mitochondrial protein Mpv17 underlies the transparent casper zebrafish.
D'Agati G, Beltre R, Sessa A, Burger A, Zhou Y, Mosimann C*, White RM*.
*co-senior authors
Dev Biol. 2017 Jul 28. pii: S0012-1606(17)30373-1. doi: 10.1016/j.ydbio.2017.07.017. [Epub ahead of print]
PMID: 28760346

 

CRISPR-Cas9 targeted disruption of the yellow ortholog in the housefly identifies the brown body locus.
Heinze SD, Kohlbrenner T, Ippolito D, Meccariello A, Burger A, Mosimann C, Saccone G, Bopp D.
Sci Rep. 2017 Jul 4;7(1):4582. doi: 10.1038/s41598-017-04686-6.
PMID: 28676649

 

Early frameshift alleles of zebrafish tbx5a that fail to develop the heartstrings phenotype
Chiavacci E, Kirchgeorg L, Felker A, Burger A, Mosimann C.
Science Matters. 2017 Apr 11. doi: 10.19185/matters.201703000011

 

Evolution of the hypoxia-sensitive cells involved in amniote respiratory reflexes.
Hockman D, Burns AJ, Schlosser G, Gates KP, Jevans B, Mongera A, Fisher S, Unlu G, Knapik EW, Kaufman CK, Mosimann C, Zon LI, Lancman JJ, Dong PDS, Lickert H, Tucker AS, Baker CVH.
Elife. 2017 Apr 7;6. pii: e21231. doi: 10.7554/eLife.21231.
PMID: 28387645

 

Clonal fate mapping quantifies the number of haematopoietic stem cells that arise during development.
Henninger J, Santoso B, Hans S, Durand E, Moore J, Mosimann C, Brand M, Traver D, Zon L.
Nat Cell Biol. 2017 Jan;19(1):17-27. doi: 10.1038/ncb3444. Epub 2016 Nov 21.
PMID: 27870830

 

An exclusive cellular and molecular network governs intestinal smooth muscle cell differentiation in vertebrates.
Gays D, Hess C, Camporeale A, Ala U, Provero P, Mosimann C, Santoro MM.
Development. 2017 Feb 1;144(3):464-478. doi: 10.1242/dev.133926. Epub 2017 Jan 3.
PMID: 28049660

 

2016:

Contemporary zebrafish transgenesis with Tol2 and application for Cre/lox recombination experiments.
Felker A, Mosimann C.
Methods Cell Biol. 2016;135:219-44. doi: 10.1016/bs.mcb.2016.01.009.
PMID: 27443928

 

CrispRVariants charts the mutation spectrum of genome engineering experiments.
Lindsay H, Burger A, Biyong B, Felker A, Hess C, Zaugg J, Chiavacci E, Anders C, Jinek M, Mosimann C*, Robinson MD*.
*co-senior authors
Nat Biotechnol. 2016 Jul 12;34(7):701-2. doi: 10.1038/nbt.3628.
PMID: 27404876

 

Maximizing mutagenesis with solubilized CRISPR-Cas9 ribonucleoprotein complexes.
Burger A*, Lindsay H*, Felker A, Hess C, Anders C, Chiavacci E, Zaugg J, Weber LM, Catena R, Jinek M, Robinson MD, Mosimann C.
*equal contribution
Development. 2016 Jun 1;143(11):2025-37. doi: 10.1242/dev.134809.
PMID:27130213

 

 

2015:

Generating and evaluating a ranked candidate gene list for potential vertebrate heart field regulators.
Musso G, Mosimann C, Panáková D, Burger A, Zhou Y, Zon LI, MacRae CA.
Genom Data. 2015 Sep 16;6:199-201. doi: 10.1016/j.gdata.2015.09.015. eCollection 2015 Dec.
PMID:26697374

Chamber identity programs drive early functional partitioning of the heart.
Mosimann C*, Panáková D*, Werdich AA, Musso G, Burger A, Lawson KL, Carr LA, Nevis KR, Sabeh MK, Zhou Y, Davidson AJ, DiBiase A, Burns CE, Burns CG, MacRae CA, Zon LI.
*equal contribution
Nat Commun. 2015 Aug 26;6:8146. doi: 10.1038/ncomms9146.
PMID: 26306682


Wnt/ß-catenin signaling is required for radial glial neurogenesis following spinal cord injury.
Briona LK, Poulain FE, Mosimann C, Dorsky RI.
Dev Biol. 2015 Jul 1;403(1):15-21. doi: 10.1016/j.ydbio.2015.03.025. Epub 2015 Apr 14.
PMID:25888075

 

Gata2b is a restricted early regulator of hemogenic endothelium in the zebrafish embryo.
Butko E, Distel M, Pouget C, Weijts B, Kobayashi I, Ng K, Mosimann C, Poulain FE, McPherson A, Ni CW, Stachura DL, Del Cid N, Espín-Palazón R, Lawson ND, Dorsky R, Clements WK, Traver D.
Development. 2015 Mar 15;142(6):1050-61. doi: 10.1242/dev.119180.
PMID:25758220

 

2014:

Novel cardiovascular gene functions revealed via systematic phenotype prediction in zebrafish.
Musso G, Tasan M, Mosimann C, Beaver JE, Plovie E, Carr LA, Chua HN, Dunham J, Zuberi K, Rodriguez H, Morris Q, Zon L, Roth FP, MacRae CA.
Development. 2014 Jan;141(1):224-35. doi: 10.1242/dev.099796.
PMID:24346703

A Cdx4-Sall4 regulatory module controls the transition from mesoderm formation to embryonic hematopoiesis.
Paik EJ, Mahony S, White RM, Price EN, Dibiase A, Dorjsuren B, Mosimann C, Davidson AJ, Gifford D, Zon LI.
Stem Cell Reports. 2013 Nov 7;1(5):425-36. doi: 10.1016/j.stemcr.2013.10.001. eCollection 2013.
PMID:24286030

 

Site-directed zebrafish transgenesis into single landing sites with the phiC31 integrase system.
Mosimann C*, Puller AC*, Lawson KL, Tschopp P, Amsterdam A, Zon LI.
*equal contribution
Dev Dyn. 2013 Aug;242(8):949-63. doi: 10.1002/dvdy.23989. Epub 2013 Jul 3.
PMID:23723152

 

2011:

Lineage regulators direct BMP and Wnt pathways to cell-specific programs during differentiation and regeneration.
Trompouki E, Bowman TV, Lawton LN, Fan ZP, Wu DC, DiBiase A, Martin CS, Cech JN, Sessa AK, Leblanc JL, Li P, Durand EM, Mosimann C, Heffner GC, Daley GQ, Paulson RF, Young RA, Zon LI.
Cell. 2011 Oct 28;147(3):577-89. doi: 10.1016/j.cell.2011.09.044.
PMID:22036566

 

Advanced zebrafish transgenesis with Tol2 and application for Cre/lox recombination experiments.
Mosimann C, Zon LI.
Methods Cell Biol. 2011;104:173-94. doi: 10.1016/B978-0-12-374814-0.00010-0.
PMID:21924163

 

Latent TGF-β binding protein 3 identifies a second heart field in zebrafish.
Zhou Y, Cashman TJ, Nevis KR, Obregon P, Carney SA, Liu Y, Gu A, Mosimann C, Sondalle S, Peterson RE, Heideman W, Burns CE, Burns CG.
Nature. 2011 May 29;474(7353):645-8. doi: 10.1038/nature10094.
PMID: 21623370

 

Ubiquitous transgene expression and Cre-based recombination driven by the ubiquitin promoter in zebrafish.
Mosimann C, Kaufman CK, Li P, Pugach EK, Tamplin OJ, Zon LI.
Development. 2011 Jan;138(1):169-77. doi: 10.1242/dev.059345.
PMID:21138979

 

2009:

Identification and functional characterization of N-terminally acetylated proteins in Drosophila melanogaster.
Goetze S*, Qeli E*, Mosimann C*, Staes A*, Gerrits B, Roschitzki B, Mohanty S, Niederer EM, Laczko E, Timmerman E, Lange V, Hafen E, Aebersold R, Vandekerckhove J, Basler K, Ahrens CH, Gevaert K, Brunner E.
*equal contribution
PLoS Biol. 2009 Nov;7(11):e1000236. doi: 10.1371/journal.pbio.1000236. Epub 2009 Nov 3.
PMID: 19885390

 

The role of Parafibromin/Hyrax as a nuclear Gli/Ci-interacting protein in Hedgehog target gene control.
Mosimann C, Hausmann G, Basler K.
Mech Dev. 2009 May-Jun;126(5-6):394-405. doi: 10.1016/j.mod.2009.02.002. Epub 2009 Feb 11.
PMID: 19368795

 

Beta-catenin hits chromatin: regulation of Wnt target gene activation.
Mosimann C, Hausmann G, Basler K.
Nat Rev Mol Cell Biol. 2009 Apr;10(4):276-86. doi: 10.1038/nrm2654. Review.
PMID: 19305417

 

2006:

Parafibromin/Hyrax activates Wnt/Wg target gene transcription by direct association with beta-catenin/Armadillo.
Mosimann C*, Hausmann G*, Basler K.
*equal contribution
Cell. 2006 Apr 21;125(2):327-41.
PMID: 16630820