Kristina Wehr Mathews

Research Associate

Dr. Kristina Wehr Mathews

Office Y11-J-38A

Tel +41 44 635 48 60

Kristina studied Optics at the University of Rochester before becoming interested in biology. Upon earning her bachelor’s degree in engineering, she spent a year at Konstanz University as an exchange student where she took classes in a range of topics including Genetics. For several years following this, she worked as a technician first in Dr. Dana Leifer’s laboratory at Yale University and then at the EMBL in Dr. Matthias Hentze’s group. She went on to study Molecular Biology at Princeton University where she was awarded her doctorate degree under the supervision of Prof. Trudi Schüpbach for her work studying female sterile mutations that disrupt axis establishment during oogenesis in Drosophila. For over eight years, Kristina has been working part time as a research assistant studying sexual size dimorphism in Drosophila in Prof. Monica Zwicky’s lab. In addition to doing research, she has supported teaching of laboratory courses. Her hope is to continue in both research and teaching in the years to come.

PUBLICATIONS

Mathews, K., Cavegn, M., and Zwicky, M. (2017) Sexual Dimorphism of Body Size Is Controlled by Dosage of the X-Chromosomal Gene Myc and by the Sex-Determining Gene tra in Drosophila

Pane, A., Wehr, K. and Schupbach, T.  (2007) Zucchini and squash encode two putative nucleases required for rasiRNA production in the Drosophila germline. Dev. Cell 6, 851-62.

Wehr, K. and Schupbach, T. (2006) Deadlock a novel protein of Drosophila, is required for germline maintenance, fusome morphogenesis and axial patterning in oogenesis and associates with centrosomes in the early embryo. Dev Bio 294, 406-417.

McKie, A. T., Marciani, P., Rolfs, A., Brennan, K., Wehr, K., Barrow, D., Miret, S., Bomford, A., Peters, T. J., Farzaneh, F. et al. (2000). A novel duodenal iron-regulated transporter, IREG1, implicated in the basolateral transfer of iron to the circulation. Mol Cell 5, 299-309.

Norvell, A., Kelley, R. L., Wehr, K. and Schupbach, T. (1999). Specific isoforms of squid, a Drosophila hnRNP, perform distinct roles in Gurken localization during oogenesis. Genes Dev 13, 864-76.

Paraskeva, E., Gray, N. K., Schlager, B., Wehr, K. and Hentze, M. W. (1999). Ribosomal pausing and scanning arrest as mechanisms of translational regulation from cap-distal iron-responsive elements. Mol Cell Biol 19, 807-16.

McKie, A. T., Wehr, K., Simpson, R. J., Peters, T. J., Hentze, M. W. and Farzaneh, F. (1998). Molecular cloning and characterisation of a novel duodenal-specific gene implicated in iron absorption. Biochem Soc Trans 26, S264.

Thermann, R., Neu-Yilik, G., Deters, A., Frede, U., Wehr, K., Hagemeier, C., Hentze, M. W. and Kulozik, A. E. (1998). Binary specification of nonsense codons by splicing and cytoplasmic translation. Embo J 17, 3484-94.

Leifer, D., Li, Y. L. and Wehr, K. (1997). Myocyte-specific enhancer binding factor 2C expression in fetal mouse brain development. J Mol Neurosci 8, 131-43.